The endocannabinoid system is a physiologic system involved in establishing and maintaining health. Endocannabinoids and their receptors are found throughout the body; in the brain, organs, connective tissues, glands, and immune cells. The main goal of this system is to provide homeostasis, or the maintenance of a stable internal environment despite fluctuations in the external environment.

Homeostasis is extremely important to your body function and health. Once you get into homeostasis you are in what is called, the “sweet spot”. When your body has achieved this sweet spot, it can run more efficiently allowing it to take care of business – staying HEALTHY.

Our endocannabinoid system has receptors that respond specifically to cannabinoids which can be found in cannabis or hemp plants. The two main endocannabinoid receptors are called CB1 and CB2.

cannabinoid is a chemical compound occurring naturally in the body, that acts on cannabinoid receptors in cells that can alter neurotransmitter release in the brain.

CB1 Receptors
These are found primarily in the brain and central nervous system. They are also found in the cerebellum and in both male and female reproductive systems.

CB2 Receptors
These are predominantly found in the immune system via peripheral nervous system. CB2 receptors appear to be responsible for the anti-inflammatory and other immune related activity.

When the endocannabinoid system is ignored, or out of homeostasis, a number of functions in the human body are impacted, such as energy level, sleep patterns, mood, eating habits and depression. These disturbances are often attributed to a chemical imbalance in the brain.

While human studies involving cannabis are slowly gaining traction, there are a number of other studies which support CBD as a possible solution to depression.


 

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